TBI-BETA BLOCKERS IN AGITATION
From NeuroRehab.wiki
SUMMARY
1. Cochrane Review: best evidence for efficacy in treating post-traumatic agitation.
2. No adverse effect on motor recovery but may cause depression and lethargy at higher doses.
3. Lipophilic agents (propranolol, metoprolol) are theoretically most effective.
4. Use is limited by hypotension and bradycardia.
5. Also useful for treatment of hyperadrenergic states common in acute TBI.
Reference(s)
Cifu, D.X. (2020). Braddom’s physical medicine and rehabilitation. Elsevier. Get it on Amazon.
Cuccurullo, S. (2019). Physical medicine and rehabilitation board review. New York: Demosmedical. Get it on Amazon.
O’Young, B., Young, M.A. and Stiens, S.A. (2008). Physical Medicine and Rehabilitation Secrets. Mosby. Get it on Amazon.
