SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)-CRITERIA

SUMMARY

American College of Rheumatology (ACR) diagnostic criteria in SLE (presented in the SOAP BRAIN MD mnemonic):
1. Serositis: pleuritis, pericarditis
2. Oral ulcers: usually painless
3. Arthritis: nonerosive
4. Photosensitivity
5. Blood disorders: low WBC, lymphs, hemolytic anemia
6. Renal disease: proteinuria, RBC casts
7. Antinuclear antibodies
8. Immunologic phenomena (+anti-dsDNA; anti- Smith [Sm] antibodies, anti-cardiolipin [ACL] abs)
9. Neurologic disorder: seizure or psychosis
10. Malar rash
11. Discoid rash

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].