SYNCOPE-DRUG CAUSES

SUMMARY

1. Those assoc. with prolonged QT interval & ventricular arrhythmia:
- Anti-arrhythmic drugs: flecanide, amiodarone, procinamide, sotalol
- Antibiotics: clarithromycin, erythromycin
- Antipsychotics: chlorpheneramine, haloperidol
- Gastric motility promoters: domperidone, cisapride

2. assoc. with bradycardia
- Beta blockers
- Certain calcium channel blockers: verapamil, diltiazem
- Digoxin

3. assoc. with postural hypotension
- Nitrates, alpha blockers, ACE inhibitors, diuretics
- Anti-Parkinson's medications

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].