SPINA BIFIDA-RISK FACTORS
From NeuroRehab.wiki
SUMMARY
1. Folate deficiency.
2. Folate antagonists: carbamazepine, valproate, trimethoprim, phenytoin, sulfasalazine.
3. Ethnicity: Hispanics.
4. Previous pregnancy with spina bifida (1 in 20 risk after first or 3-5% chance; after 2 children risk is 1 in 2); patient with spina bifida has a 2.5% risk of having a child with similar issue.
5. Maternal diabetes.
6. Maternal hypothermia.
Reference(s)
Cifu, D.X. (2020). Braddom’s physical medicine and rehabilitation. Elsevier. Get it on Amazon.
Cuccurullo, S. (2019). Physical medicine and rehabilitation board review. New York: Demosmedical. Get it on Amazon.
O’Young, B., Young, M.A. and Stiens, S.A. (2008). Physical Medicine and Rehabilitation Secrets. Mosby. Get it on Amazon.
