RENAL PHYSIOLOGY-PROXIMAL TUBULE

SUMMARY

1. 65% of filtered Na+, Cl^-, HCO₃^- and water is reabsorbed in the proximal tubule (PT).

2. The PT is very permeable to water, which is reabsorbed in a 1:1 fashion with Na+

3. For each H+ that is secreted, one Na+ and one HC03- are reabsorbed.

SOLUTES ARE ABSORBED VIA 4 MECHANISMS

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].