RENAL PHYSIOLOGY-LOOP OF HENLE

SUMMARY

1. First half (descending) handles reabsorption of 20% of remaining water (following an osmotic gradient) and a little bit of solutes.

2. The second half (ascending) handling reabsorption of only solutes via active transport, driving the actions of the first half.

3. In the thin ascending segment, NaCl passively diffuses into the interstitium.

SOLUTES ARE ABSORBED VIA 3 MECHANISMS

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].