RENAL PHYSIOLOGY-HENDERSON HASSELBACH EQUATION

SUMMARY

1. The Henderson-Hasselbach equation:


2. It is derived from the bicarbonate buffer equation:


3. This equation tells us that the body has only 2 ways to control the serum pH: (1) Regulate the respiratory rate and tidal volume, thus, control the PCO₂ (2) regulate the kidney's reabsorption of HC03^-

Reference(s)

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Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].