RENAL INX-PROTEINURIA

SUMMARY

1. Proteinuria is an important indicator of underlying renal pathology; normal 24-hour urine protein is < 150 mg.

2. Greater than 2 g/d indi­cates significant glomerular pathology.

3. Medullary cystic disease and obstructive uropathy are the only exceptions in which there can be pathology and a normal urine sediment with minimal proteinuria.

4. Transient proteinuria is common in people during a febrile illness, after strenuous exercise, and in patients with HF and COPD.

5. Estimated with spot urine protein:creatinine ratio.

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].