PITUITARY-TUMORS

SUMMARY

Abnormal proliferation of cells from anterior pituitary:

1. Lactotrophs (PRL): most common macroadenomas

2. Gonadotrophs (LH & FSH): common macroadenomas, present(s) with mass effect +/- hormonally silent / hyposecretion / hypersecretion

3. Corticotrophs (ACTH): Cushing's disease

4. Somatotrophs (GH): acromegaly

5. Thyrotrophs (TRH): hyperthyroidism (uncommon)

6. Mixed cell types (PRL & GH): hyperprolactinemia & acromegaly

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].