PITUITARY-ACROMEGALY CLINICAL FEATURES

SUMMARY

1. Insidious onset, patients symptomatic in their 30s & 40s.

2. Coarse facial features.

3. Deeping of voice (after puberty).

4. Pronounced jaw growth & dental problems.

5. Sleep apnoea.

6. Enlarged hands & feet.

7. Carpal tunnel syndrome.

8. Skin tags.

9. Acanthosis nigricans.

10. Excessive sweating & body odor.

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].