OSTEOPOROSIS-BONE FORMATION OR RESORPTION

SUMMARY

BONE FORMATION FACTORS
1. Weight-bearing activity
2. Testosterone
3. Estrogen
4. Growth hormone
5. Euthyroid state

BONE RESORPTION FACTORS
1. Lack of weight-bearing activity
2. Endogenous/exogenous cortisol excess
3. Hyperthyroidism
4. Primary/secondary/tertiary hyperparathyroidism
5. Acidosis (stimulates PTH secretion)

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].