NEUROPATHY-DIABETIC

SUMMARY

1. Not only assoc. with DM but also IGT, produces length-dependent neuropathy. Occurs in 25% of patients with idiopathic neuropathy.

SYMMETRIC PRESENTATION
2. Distal, symmetric axonal sensorimotor neuropathy (commonest presentation)

3. Small-fiber, painful neuropathy: common feature of both pre-diabetic and diabetic neuropathy (image a)

4. Autonomic neuropathy (image d)

ASYMMETRIC PRESENTATION
5. Cranial neuropathy: pupil-sparing CN III involvement

6. Multifocal or entrapment: carpal tunnel syndrome (image c)

7. Radicular or plexus involvement: produces diabetic amyotrophy (image d)

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].