MULTIPLE SCLEROSIS-COGNITIVE IMPAIRMENT

SUMMARY

1. More prevalent in chronic progressive MS.

2. There is some correlation between plaque load and dementia.

3. Frontal lobe dysfunction is commonly seen: problems with initiation, poor insight and planning.

4. Prefrontal dysfunction may exhibit as inappropriate behaviour, excessive talking and poor judgement.

5. Counselling & cognitive rehabilitation are important to minimise the effect of deficits on ADLs.

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].