MEDICATION-MIDODRINE

From NeuroRehab.wiki

SUMMARY

1. Great drug! Pro-drug: desglymidodrine.

2. Alpha-1 receptor agonist: works on arteries & veins.

3. Peak action in 1-2 hrs post-oral intake, lasting 3-4 hrs. 94% bioavailability.

4. Useful in the ward for patients with sepsis who have been adequately fluid resuscitated. Can also be used in postural hypotension.

5. Dosage: 10 mg Q6h - 20 mg Q6h; just don't send patients home on it! Wean over 3 days.