LYMPHEDEMA

SUMMARY

1. Lymphedema results from impaired lymph drainage, resulting in accumulation of protein in the interstitium. This changes the colloidal pressure, and detracts fluid into the interstitial space.

2. 9L of lymph flows back into venous circulation each day: 40% from liver, 40% from gut, 20% from periphery. 30% peripheral fluid returns at the nodal level.

3. There is a lymphatic component to all types of chronic oedema (> 3 months).

4. UL lymphedema is most common after breast cancer, in patients who have had a nodal dissection & radiotherapy.

5. Usually develops over an extended period of time, post mastectomy or lumpectomy in up to 1/3 of women.

6. LL lymphedema is associated with uterine CA, prostate CA, lymphoma, or melanoma.

Reference(s)

Cifu, D.X. (2020). Braddom’s physical medicine and rehabilitation. Elsevier. Get it on Amazon.
Cuccurullo, S. (2019). Physical medicine and rehabilitation board review. New York: Demosmedical. Get it on Amazon.
O’Young, B., Young, M.A. and Stiens, S.A. (2008). Physical Medicine and Rehabilitation Secrets. Mosby. Get it on Amazon.