IONS-INTRACELLULAR FLUID (ICF)

SUMMARY

1. 98% of total body potassium is intracellular, concentration ~150 mmol/l

2. K⁺, Na⁺, Mg⁺ are the major cations present

3. Organic phosphates are the major anions

4. When ECF K⁺ is < 3.0, intracellular K⁺ will diffuse out, but H⁺ will diffuse in, hence the intracellular net charge will remain constant

5. 66% of total body water is intracellular

Reference(s)

Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education