GLOMERULONEPHRITIS-CLASSIFICATION (NEPHRITIC VS NEPHROTIC)

SUMMARY

1. Proteinuria < 2gm/day: nephritic syndrome
- Low complement, systemic presentation: SLE, endocarditis, cryoglobulinemia
- Low complement, renal presentation: PIGN, MPGN
- Normal complement, systemic presentation: Thrombotic Thrombocytopenic Purpura (TTP), Goodpastures
- Normal complement, renal presentation: IgA, Alport

2. Proteinuria > 3.5gm/day: nephrotic syndrome
- Systemic presentation: DM, amyloidosis
- Renal presentation: minimal change disease, FSGS, membranous disease

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].