DEMENTIA-CORTICAL VS SUBCORTICAL

SUMMARY

SUBCORTICAL DEMENTIAS
1. Heterogeneous group of disorders that share primary pathology in subcortical structure and a characteristic pattern of neuropsychologic impairment.

2. Characterized by: impaired problem-solving, personality changes (apathy, inertia, depression), slowed thought processes (bradyphrenia), frontal dysfunction (disinhibition, personality change).

3. Frontal signs result from a disconnection of the frontal cortex from the basal ganglia.

CORTICAL DEMENTIAS
4. Group of disorders due to cortical pathology.

5. Characterized by: memory & language deficits.

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].