AUTOREGULATION-HISTAMINE
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SUMMARY
1. Derived from histidine, found in granules of basophils & mast cells.
2. Released in response to trauma & allergic reactions.
3. Functions: visceral smooth muscle contraction, vascular smooth muscle relaxation (through the action of NO), vasodilation, increased capillary permeability, attracts leukocytes.
Reference(s)
Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education
