AUTOREGULATION-HEART FAILURE
From NeuroRehab.wiki
SUMMARY
1. Heart failure occurs when CO is inadequate for the needs of tissues.
2. Systolic failure: stroke volume is reduced, leading to reduction in EF and increased end-systolic volume.
3. Diastolic failure: EF is initially maintained but ventricular compliance is reduced, leading to inadequate preload and stroke volume.
4. High-output cardiac failure: relative CO is reduced due to shunting or other pathologic processes.
5. Initial response to any form of failure is cardiac remodeling, increased secretion of renin & aldosterone leading to Na & water retention.
Reference(s)
Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education
