ACUTE KIDNEY INJURY (AKI)

SUMMARY

1. AKI is defined as an increase in the serum creatinine by 0.3 mg/dL or by 1.5-fold over baseline within 48 hours, or by oliguria (urine output < 0.5 mL/kg/hr) for at least 6 hours.
2. Anuria is <50 mL/d.
3. Aetiology: pre-renal, post-renal, intrinsic.
4. Classification: non-oliguric, oliguric, or anuric.


Image: Johnson & Feehaly, Comprehensive Clinical Nephrology 2007

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].