ACUTE CORONARY SYNDROME-FIBRINOLYTIC THERAPY CI

SUMMARY

ABSOLUTE CI
1. Previous hemorrhagic stroke at any time; other cerebrovascular events within 1 year
2. Intracranial neoplasm
3. Active internal bleeding
4. Suspected aortic dissection

RELATIVE CI
5. Persistent BP > 180/110
6. Remote non-hemorrhagic CVA (> 1 year)
7. Current use of anticoagulants with INR > 2-3; bleeding diathesis
8. Recent (2-4 weeks) major trauma or surgical procedure
9. Noncompressible vascular puncture
10. Previous exposure to streptokinase/anistreplase
11. Pregnancy
12. Active peptic ulcer

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].