LOC-OVER SEDATION MANAGEMENT

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Revision as of 11:11, 19 December 2022 by Dr Appukutty Manickam (talk | contribs) (Imported from text file)

TOPIC SUMMARY


1. Most common cause of LOC is over-sedation
2. Most commonly due to opioid toxicity, managed with Naloxone/Flumazenil
3. Note that IM Naloxone lasts longer (approx. 2 hrs)! Can be used if IV Naloxone infusion is not an option
4. Naloxone infusion: 1 mg to 100 mL, 10-40 mL/hr
5. Flumazenil infusion: 0.1-0.5 mg, 10-40mL/hr

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Reference(s)

Gale, M., Grantham, H., Morley, P. and Parr, M. (2016). Advanced Life Support Level 1: 3rd Australian Edition. Australian Resuscitation Council.
American College Of Surgeons. Committee On Trauma (2012). ATLS : student course manual. Chicago, Ill.: American College Of Surgeons.