PARKINSONS (MILD TO MODERATE) Tx-DOPAMINE AGONISTS

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SUMMARY

1. Non-ergot derived dopamine agonists (ropinirole and pramipexole) can be useful as mono-therapy, but 60% of patients will require adjunctive L-dopa after 4 years.

2. Know that these dopa agonists, ropinirole and pramipexole, are associated with impulse control disorders, such as hypersexuality, compulsive shopping, and pathological gambling.


Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].