RENIN ANGIOTENSIN SYSTEM-TISSUE SYSTEM
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Revision as of 10:51, 2 January 2023 by Dr Appukutty Manickam (talk | contribs) (Imported from text file)
SUMMARY
1. Independent of circulating RAS.
2. Intrarenal RAS: most important tissue RAS.
3. Angiotensin II in renal interstitial fluid is approximately 1000x higher than in the systemic system.
4. Very sensitive to sodium intake.
5. Causes vasoconstriction and anti-natriuresis.
Reference(s)
Barrett, K.E., Barman, S.M., Boitano, S., Brooks, H.L., Weitz, M., Brian Patrick Kearns, Ganong, W.F. and Mcgraw-Hill Education (Firm (2016). Ganong’s review of medical physiology. 25th ed. New York: Mcgraw Hill Education.
Hall, J.E. and Hall, M.E. (2020). Guyton And Hall Textbook Of Medical Physiology. 14th ed. S.L.: Elsevier - Health Science.
West, J.B. and Luks, A.M. (2021). West’s Pulmonary Pathophysiology. Lippincott Williams & Wilkins.
