SJOGREN'S SYNDROME-PRESENTATION
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SUMMARY
Mucus glands are infiltrated by lymphocytes and plasma cells leading to atrophy and fibrosis.
Presentation:
1. Dry eyes - conjunctivitis, corneal ulcers
2. Dry mouth
3. Chest infection - due to reduced mucus production
4. Kidneys - RTA, nephrogenic DI
5. Genital tract - atrophic vaginitis
6. Pseudolymphoma - lymphadenopathy and splenomegaly which can progress to non-Hodgkin's lymphoma
Reference(s)
Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
