MEDICATION-MIDODRINE
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Revision as of 11:26, 19 December 2022 by Dr Appukutty Manickam (talk | contribs) (Imported from text file)
SUMMARY ARTICLE
1. Great drug! Pro-drug: desglymidodrine.
2. Alpha-1 receptor agonist: works on arteries & veins.
3. Peak action in 1-2 hrs post-oral intake, lasting 3-4 hrs. 94% bioavailability.
4. Useful in the ward for patients with sepsis who have been adequately fluid resuscitated. Can also be used in postural hypotension.
5. Dosage: 10 mg Q6h - 20 mg Q6h; just don't send patients home on it! Wean over 3 days.
Reference(s)
Gale, M., Grantham, H., Morley, P. and Parr, M. (2016). Advanced Life Support Level 1: 3rd Australian Edition. Australian Resuscitation Council.
American College Of Surgeons. Committee On Trauma (2012). ATLS : student course manual. Chicago, Ill.: American College Of Surgeons.
