RENAL INX-PROTEINURIA
SUMMARY
1. Proteinuria is an important indicator of underlying renal pathology; normal 24-hour urine protein is < 150 mg.
2. Greater than 2 g/d indicates significant glomerular pathology.
3. Medullary cystic disease and obstructive uropathy are the only exceptions in which there can be pathology and a normal urine sediment with minimal proteinuria.
4. Transient proteinuria is common in people during a febrile illness, after strenuous exercise, and in patients with HF and COPD.
5. Estimated with spot urine protein:creatinine ratio.
Reference(s)
Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].