Difference between revisions of "LOC-OVER SEDATION MANAGEMENT"
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===== [[Summary Article|'''SUMMARY''']] ===== | ===== [[Summary Article|'''SUMMARY''']] ===== | ||
1. Most common cause of LOC is over- | 1. Most common cause of LOC is over-sedation | ||
<br/>2. Most commonly due to opioid toxicity, managed with Naloxone/Flumazenil | <br/>2. Most commonly due to opioid toxicity, managed with Naloxone/Flumazenil | ||
<br/>3. Note that IM Naloxone lasts longer (approx. 2 hrs)! Can be used if IV Naloxone infusion is not an option | <br/>3. Note that IM Naloxone lasts longer (approx. 2 hrs)! Can be used if IV Naloxone infusion is not an option | ||
<br/>4. | <br/>4. Naloxone infusion: 1 mg to 100 mL, 10-40 mL/hr | ||
<br/>5. | <br/>5. Flumazenil infusion: 0.1-0.5 mg, 10-40mL/hr | ||
<br/> | <br/> | ||
<br/>[[Image:paste-96e9843f97124e0f7852f4a914795abb63f30f24.jpg]] | <br/>[[Image:paste-96e9843f97124e0f7852f4a914795abb63f30f24.jpg]] | ||
Latest revision as of 11:31, 1 January 2023
SUMMARY
1. Most common cause of LOC is over-sedation
2. Most commonly due to opioid toxicity, managed with Naloxone/Flumazenil
3. Note that IM Naloxone lasts longer (approx. 2 hrs)! Can be used if IV Naloxone infusion is not an option
4. Naloxone infusion: 1 mg to 100 mL, 10-40 mL/hr
5. Flumazenil infusion: 0.1-0.5 mg, 10-40mL/hr
