Difference between revisions of "RENAL TUBULAR ACIDOSIS (RTA)-SUMMARY"
(Imported from text file) |
(Imported from text file) |
||
| Line 20: | Line 20: | ||
==Reference(s)== | ==Reference(s)== | ||
Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. | Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. [https://amzn.to/3YHrI6K Get it on Amazon.] | ||
<br/>Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. [https://amzn.to/3k7WSW0 Get it on Amazon.] | |||
<br/>Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy. | <br/>Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy. | ||
<br/>Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021]. | <br/>Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021]. | ||
Latest revision as of 20:03, 13 March 2023
SUMMARY
TYPE 1
- distal
- problem with H/K-ATPase of the intercalated cells in the late distal tubule and cortical collecting ducts that results in failure to acidify the urine
- serum: metabolic acidosis, hypokalemia
- urine: urine alkaline, calciuria
TYPE 2
- proximal
- decreased resorption of HCO3- in the proximal tubule (bicarbonate wasting)
- serum: metabolic acidosis, hyponatremia, hypokalemia,
- urine: urine variable, glucosuria, amino aciduria, and wasting of other solutes, including Mg, uric acid, and phosphorus
TYPE 4
- distal, aldosterone resistance
- decreased Na+/K+ exchange in the late distal dubule and cortical collecting ducts
- serum: metabolic acidosis, hyperkalemia
- urine: alkaline, calciuria
Reference(s)
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
