Difference between revisions of "MEDICATION-MIDODRINE"

Revision as of 11:11, 19 December 2022

TOPIC SUMMARY

1. Great drug! Pro-drug: desglymidodrine.

2. Alpha-1 receptor agonist: works on arteries & veins.

3. Peak action in 1-2 hrs post-oral intake, lasting 3-4 hrs. 94% bioavailability.

4. Useful in the ward for patients with sepsis who have been adequately fluid resuscitated. Can also be used in postural hypotension.

5. Dosage: 10 mg Q6h - 20 mg Q6h; just don't send patients home on it! Wean over 3 days.

Reference(s)

Gale, M., Grantham, H., Morley, P. and Parr, M. (2016). Advanced Life Support Level 1: 3rd Australian Edition. Australian Resuscitation Council.
American College Of Surgeons. Committee On Trauma (2012). ATLS : student course manual. Chicago, Ill.: American College Of Surgeons.

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 <div>1. Great drug! Pro-drug: desglymidodrine.<div><br></div><div>2. Alpha-1 receptor agonist: works on arteries & veins.</div><div><br></div><div>3. Peak action in 1-2 hrs post-oral intake, lasting 3-4 hrs. 94% bioavailability.</div><div><br></div><div>4. Useful in the ward for patients with sepsis who have been adequately fluid resuscitated. Can also be used in postural hypotension. </div><div><br></div><div>5. Dosage: 10 mg Q6h - 20 mg <span style=color: var(--field-fg); background: var(--field-bg);>Q6h; just don't send patients home on it! Wean over 3 days.</span></div>