Difference between revisions of "SJOGREN'S SYNDROME-PRESENTATION"

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<br/>Presentation:
<br/>Presentation:
<br/>
<br/>
<br/>1. Dry eyes - conjunctivitis, corneal ulcers
<br/>1. Dry eyes: conjunctivitis, corneal ulcers
<br/>2. Dry mouth
<br/>2. Dry mouth
<br/>3. Chest infection - due to reduced mucus production
<br/>3. Chest infection: due to reduced mucus production
<br/>4. Kidneys - RTA, nephrogenic DI
<br/>4. Kidneys: RTA, nephrogenic DI
<br/>5. Genital tract - atrophic vaginitis
<br/>5. Genital tract: atrophic vaginitis
<br/>6. Pseudolymphoma - lymphadenopathy and splenomegaly which can progress to non-Hodgkin's lymphoma
<br/>6. Pseudolymphoma: lymphadenopathy and splenomegaly which can progress to non-Hodgkin's lymphoma




==Reference(s)==
==Reference(s)==
Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. [https://amzn.to/3YHrI6K Get it on Amazon.]
<br/>Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. [https://amzn.to/3k7WSW0 Get it on Amazon.]
<br/>Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
<br/>Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
<br/>Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
<br/>Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].

Latest revision as of 02:30, 21 March 2023

SUMMARY

Mucus glands are infiltrated by lymphocytes and plasma cells leading to atrophy and fibrosis.

Presentation:

1. Dry eyes: conjunctivitis, corneal ulcers
2. Dry mouth
3. Chest infection: due to reduced mucus production
4. Kidneys: RTA, nephrogenic DI
5. Genital tract: atrophic vaginitis
6. Pseudolymphoma: lymphadenopathy and splenomegaly which can progress to non-Hodgkin's lymphoma


Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].