View source for STROKE-tPA EXCLUSION CRITERIA (RELATIVE CONTRAINDICATIONS)

===== [[Summary Article|'''SUMMARY''']] =====
1. Severe neurologic impairment with NIHSS score &gt; 22.2
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<br/>2. Age &lt; 18 years or &gt; 80 years
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<br/>3. Malignant cerebral infarction
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<br/>4. Hx of major surgery within 14 days
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<br/>5. Hx of significant GIT hemorrhage within 21 days
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<br/>6. Hx of stroke or TBI within 3 months
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<br/>7. Hx of recent MI within 30 days
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<br/>8. Advanced, terminal disease (e.g. cancer)
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<br/>9. Pregnancy is not an absolute contraindication


==Reference(s)==
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. [https://amzn.to/3YHrI6K Get it on Amazon.]
<br/>Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. [https://amzn.to/3k7WSW0 Get it on Amazon.]
<br/>Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
<br/>Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].

[[Category:Stroke]]
[[Category:Neurology]]
[[Category:Medicine]]