NEUROPATHIC PAIN-INTRODUCTION
SUMMARY
DEFINITION
1. Pain arising as a direct consequence of a lesion or disease affecting the somatosensory system[1]
2. Jensen TS, Baron R, Haanpää M, et al. A new definition of neuropathic pain. Pain 2011; 152: 2204–05.
3. Jensen TS, Baron R. Translation of symptoms and signs into mechanisms in neuropathic pain. Pain 2003; 102: 1–8.
4. Woolf CJ. Dissecting out mechanisms responsible for peripheral neuropathic pain: implications for diagnosis and therapy. Life Sci 2004; 74: 2605–10.
5. Von Hehn CA, Baron R, Woolf CJ. Deconstructing the neuropathic pain phenotype to reveal neural mechanisms. Neuron 2012; 73: 638–52.
.
CHARACTERISTICS[2]
[3][4][5]2. Pain in an area with partial or complete sensory loss
3. Different types of evoked pain
4. Specific descriptors such as burning pain
5. Increased pain after repetitive stimulation
6. Pain persisting after stimulation
7. There may be associated allodynia and/or hyperalgesia
Reference(s)
- ↑ Treede RD, Jensen TS, Campbell JN et al. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology 70(18), 1630–1635 (2008).
- ↑ Jensen TS, Baron R, Haanpää M, et al. A new definition of neuropathic pain. Pain 2011; 152: 2204–05.
- ↑ Jensen TS, Baron R. Translation of symptoms and signs into mechanisms in neuropathic pain. Pain 2003; 102: 1–8.
- ↑ Woolf CJ. Dissecting out mechanisms responsible for peripheral neuropathic pain: implications for diagnosis and therapy. Life Sci 2004; 74: 2605–10.
- ↑ Von Hehn CA, Baron R, Woolf CJ. Deconstructing the neuropathic pain phenotype to reveal neural mechanisms. Neuron 2012; 73: 638–52.
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