EXTRACELLULAR FLUID (ECF)

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SUMMARY

1. Think of ECF like an ‘internal sea’, a medium for exchange O2 & waste, crucial for cell function & survival.

2. ECF is iso-osmotic with ICF at osmotic equilibrium

3. ECF is best measured using inulin, a polysaccharide, MW5200

4. Transcellular water = that component of ECF that has been processed through cells into special compartments (aqueous humour, CSF, synovial fluid).


Reference(s)

Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education