CARDIAC OUTPUT-DETERMINANTS OF EDV

SUMMARY

REDUCED END-DIASTOLIC VOLUME
1. Reduced ventricular compliance (e.g. MI, infiltrative disease).
2. Pericardial effusion.
3. Reduced venous return to heart, e.g. standing.

INCREASED END-DIASTOLIC VOLUME
4. Stronger atrial contraction.
5. Negative intra-thoracic pressure during inspiration.
6. Increased venous return to heart, e.g. muscle pumps during exercise.

Reference(s)

Barrett, K.E., Barman, S.M., Brooks, H.L., X, J. and Ganong, W.F. (2019). Ganong’s review of medical physiology. 26th ed. New York: Mcgraw-Hill Education