SERONEGATIVE ARTHRITIS-PSORIATIC ARTHRITIS MGM

SUMMARY

NON-PHARMACOLOGICAL
1. Splinting, immobilisation during acute exacerbations; slow passive ROM, heat & massage

ANTI-INFLAMMATORY AGENTS
2. Paracetamol, NSAIDs
3. Steroid injection (as only few joints involved)

NON-BIOLOGIC DMARDs
4. Sulfasalazine (well tolerated, not immunosuppressive), methotrexate, leflunomide

BIOLOGIC DMARDs

5. TNF-alpha antagonists: infliximab, adalimumab, golinumab
6. Soluble TNF receptor: etanercept

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].