DIABETES INSIPIDUS-CAUSES

SUMMARY

A. NEUROGENIC (DECREASED PRODUCTION OF ADH)
1. Acquired: trauma, eosinophilic granuloma, sarcoidosis, granulomatosis with polyangitis, CA, Sheehan syndrome, idiopathic
2. Genetic

B. NEPHROGENIC (DECREASED RESPONSE TO ADH)
3. Acquired: lithium, any causes of severe hypercalcemia (> 11 mg/dL)
4. Genetic: mutations in the ADH receptor or aquaporin

C. OTHER CAUSES
5. Sjogren's
6. Sickle cell disease

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].