VASCULITIS-TAKAYASU ARTERITIS

SUMMARY

1. Primarily affects young women (< 40), particularly of Asian descent.

2. Inflammatory phase: PUO; pulseless phase: UL claudication, strokes, TIA, or renovascular HTN with bruits.

3. MRA can demonstrate large artery narrowing, referred to as "beading" or "string of pearls," and/or characteristic aneurysms.

4. Treat with glucocorticoids (main) or DMARDs.

5. Revascularization with angioplasty, stenting, or bypass surgery may be needed for severely stenotic arteries when the acute inflammatory phase is controlled.

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].