STROKE-PROTHROMBOTIC (YOUNG STROKE) SCREEN

SUMMARY

1. Activated protein C resistance, Factor V Leiden mutation

2. Prothrombin gene mutation

3. Protein C, S, antithrombin levels to look for deficiencies

4. Antiphospholipid syndrome: lupus anticoagulant antibodies, anti-cardiolipin antibodies, anti-beta-2-glycoprotein antibodies

5. Summary of young stroke work up: CRP, ESR, ENA, ANA, ANCA, dsDNA, C3, C4, Syphilis serology, Hep B/Hep C, HIV, VZV serology, Homocystiene, Prothrombin gene, Factor V Leiden, Protein C, Protein S, Antithrombin 3, Lupus anticoagulant, anti-cardiolipin antibody, B2-glycoprotien

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
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Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].