STROKE-ECR (ENDOVASCULAR CLOT RETRIEVAL)
SUMMARY
1. Thrombectomy devices can be useful in achieving mechanical recanalization or in combination with pharmacological fibrinolysis in selected patients.
2. Thrombolysis may be performed whilst awaiting clot retrieval.
3. Can be performed within 6-24 hours: earlier for ICA, M1 or tandem lesions.
4. EXTEND IA trial showed superior outcomes to TPA alone.
5. Tenecteplase improves reperfusion prior to thrombectomy versus alteplase, EXTEND-IA TNK trial[1].
Reference(s)
- ↑ Campbell, B.C., Mitchell, P.J., Churilov, L., Yassi, N., Kleinig, T.J., Dowling, R.J., Yan, B., Bush, S.J., Dewey, H.M., Thijs, V. and Scroop, R., 2018. Tenecteplase versus alteplase before thrombectomy for ischemic stroke. New England Journal of Medicine, 378(17), pp.1573-1582.
Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
