MULTIPLE SCLEROSIS-INTRODUCTION

SUMMARY

1. MS is a chronic demyelinating disease of the CNS that begins between the ages of 20-30 yrs.

2. Women are affected more often than men (3:1); more common in temperate climates.

3. 4 types: (a) relapsing-remitting [RLRM] (b) secondary progressive (c) primary progressive (d) benign multiple sclerosis.

4. The relapsing-remitting type (initially normal but later on with residual deficit between spells) can transform into the progressive type.

5. 85% of cases are initially RLRM, after several years, transform to the progressive type.

Reference(s)

Wilkinson, I., Furmedge, D. and Sinharay, R. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press. Get it on Amazon.
Feather, A., Randall, D. and Waterhouse, M. (2020). Kumar And Clark’s Clinical Medicine. 10th ed. S.L.: Elsevier Health Sciences. Get it on Amazon.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].