ATN-DRUGS & ATN
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Revision as of 11:48, 31 January 2023 by Dr Appukutty Manickam (talk | contribs) (Imported from text file)
SUMMARY
1. Amphotericin B causes ATN at a cumulative dose at > 3 gm, causing Type 1 & 2 RTA.
2. Aminoglycosides (AG) cause proximal tubule damage, GFR begins to fall 5-7 days after the start. OD dosing is less nephrotoxic than multi-daily doses. Gentamicin is the most toxic AG.
3. Cisplatin causes a magnesiuria and hypomagnesemia.
Reference(s)
Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
