ALDOSTERONE-SYSTEMIC EFFECTS
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Revision as of 11:48, 31 January 2023 by Dr Appukutty Manickam (talk | contribs) (Imported from text file)
SUMMARY
1. Activation of inflammatory cascade and production of pro-inflammatory cytokines.
2. Contributes to insulin resistance.
3. Promote cardiac fibrosis, hence, blockade with spironolactone is recommended in cardiac failure.
4. Also potentially involved in metabolic syndrome
Reference(s)
Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].
