VASCULITIS-TAKAYASU ARTERITIS

SUMMARY

1. Primarily affects young women (< 40), particularly of Asian descent.

2. Inflammatory phase - PUO; pulseless phase - UL claudication, strokes, TIA, or renovascular HTN with bruits.

3. MRA can demonstrate large artery narrowing, referred to as "beading" or "string of pearls," and/or characteristic aneurysms.

4. Treat with glucocorticoids (main) or DMARDs.

5. Revascularization with angioplasty, stenting, or bypass surgery may be needed for severely stenotic arteries when the acute inflammatory phase is controlled.

Reference(s)

Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].