AUTOREGULATION-MEDULLARY CONTROL

SUMMARY

1. Nucleus Tractus Solitarius (NTS) is the site of termination of baroreceptor afferent fibers.
2. Excitatory input to sympathetic nerves: from rostral ventrolateral medulla (RVLM) AKA vasomotor area.
3. Fibers descend to the thoraco-lumbar intermedeolateral grey column (thoraco-lumbar outflow/ILM).

CONTROL OF RVLM
4. Arterial baroreceptors, aortic & carotid chemoreceptors, fibers from other parts of nervous system.
5. Descending tracts from limbic cortex that relay in the hypothalamus.
6. Inflation of the lungs causes vasodilatation & decrease in BP via vagal afferents that inhibit vasomotor discharge.
7. Pain causes a rise in BP via reticular formation.



Image: Dr. Appukutty Manickam.

Reference(s)

Barrett, K.E., Barman, S.M., Boitano, S., Brooks, H.L., Weitz, M., Brian Patrick Kearns, Ganong, W.F. and Mcgraw-Hill Education (Firm (2016). Ganong’s review of medical physiology. 25th ed. New York: Mcgraw Hill Education.
Hall, J.E. and Hall, M.E. (2020). Guyton And Hall Textbook Of Medical Physiology. 14th ed. S.L.: Elsevier - Health Science.
West, J.B. and Luks, A.M. (2021). West’s Pulmonary Pathophysiology. Lippincott Williams & Wilkins.