RHABDOMYOLYSIS-CAUSES

SUMMARY

1. Crush injuries (compartment syndromes), coma, or traumatic immobilisation
2. Prolonged surgeries
3. Strenuous exercise in extreme heat
4. Generalised seizures
5. Heat stroke
6. Severe volume contraction
7. Drugs: cocaine, amphetamines, statins, colchicines, anesthetics causing malignant hyperthermia, neuroleptic malignant syndrome
8. Infections: usually viral, especially influenza A and B
9. Endocrinopathies: DKA, hypothyroidism, hyperthyroidism, and pheo
10. Electrolyte abnormalities: severe hypokalemia, hypophosphatemia (in alcoholics during re-feeding syndrome)

Reference(s)

Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].