GLOMERULONEPHRITIS-PATHOLOGY

SUMMARY

1. The glomerulus is a specialized capillary plexus surrounded by the Bowman capsule.

2. The capillary walls filter blood, allowing an ultrafiltrate of the plasma to pass into the Bowman capsule, which collects the ultrafiltrate in the tubules for further process­ing.

3. The wall of the glomerulus filters with: endothelial cells, glomerular basement membrane (GBM), slit pores between the epithelial cell foot processes.

4. Glomerular diseases primarily affect the glomerular apparatus only and are collectively termed glomerulo­nephritides; presentation: nephritic, nephrotic syndromes, asymptomatic haematuria.



Image: Jeanette, J.C. (2007). Primer on the pathologic basis of renal disease. In J.C. Jeanette (Ed.), Hepinstall's Pathology of the Kidney, 6th Edition

Reference(s)

Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].