SYSTEMIC SCLEROSIS-GI

SUMMARY

1. Diffuse SSC: wide-mouthed diverticula.

2. Limited SSC: eusophageal dysmotility.

3. Both types: gastroparesis, GORD, chronic esophagitis, strictures, Barrett disease, dysphagia, pseudo-obstruction, malabsorption.

4. Mucosal telangiectasias may be present throughout the GIT. Telangiectasias in the stomach can lead to bleeding and iron-deficiency anemia. This syndrome is called gastric antral vascular ectasia (GAVE).

5. Treat with PPI and prokinetics such as erythromycin.

Reference(s)

Wilkinson, I. (2017). Oxford handbook of clinical medicine. Oxford: Oxford University Press.
Hannaman, R. A., Bullock, L., Hatchell, C. A., & Yoffe, M. (2016). Internal medicine review core curriculum, 2017-2018. CO Springs, CO: MedStudy.
Therapeutic Guidelines. Melbourne: Therapeutic Guidelines Limited. https://www.tg.org.au [Accessed 2021].