MEDICATION-ATROPINE

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SUMMARY ARTICLE


1. Parasympathetic antagonist that increases HR by blocking vagal tone.
2. Indications: symptomatic bradycardia with haemodynamic compromise. A bradycardic patient with no pulse should be treated as for PEA.
3. SE: dysthymia, HTN, urinary retention, delirium, hyperthermia in large doses.

DOSAGE 
4. Rapid boluses of 500-600 mcg every 3-5 min up to a maximum of 3 mg.
5. Do not give slowly or boluses < 500 mcg as this may irritate vagal fibres and cause a paradoxical reduction in HR.
6. Contraindicated in heart transplant patients as denervated hearts do not respond and may cause a heart block.